High serum concentrations of TNF-α, IL6, CRP, osteoprotegerin, fibrinogen, sICAM1, sTNFR2, and myeloperoxidase were shown to be associated with CKD status, higher cystatin C quartiles, and higher urinary albumin-to-creatinine ratio quartiles (7, 12). The gene discussed is CRP; the disease is chronic kidney disease.