OSBP and amyotrophic lateral sclerosis: A serum and CSF study was conducted in non-riluzole ALS patients, riluzole-treated ALS patients and healthy subjects to measure 24S-hydroxycholesterol, 27-hydroxycholesterol, oxysterols in the brain and 25-hydroxycholesterol levels (LXR and OSBP1 ligands) (Kim et al., 2017).