Compared with the non-infection treatment (w/o PRRSV), PRRSV infection constantly upregulated the RACK1 expression over a 60 hours duration (Fig. 3B, non-transfection and siScramble treatments), continuously induced the phosphorylation of IκBa and p65 (Fig. 3D,F), which became more significant with longer infection time. Here, RACK1 is linked to infection.