To determine the role of Snail in STK17B-mediated migration and invasion in HCC, SMMC7721 cells transfected with Lv-STK17B plus Lv-shSnail and HCCLM3 cells transfected with Lv-shSTK17B plus Lv-Snail were used to perform further experiments. The gene discussed is STK17B; the disease is hepatocellular carcinoma.