To determine the role of Snail in STK17B-mediated migration and invasion in HCC, SMMC7721 cells transfected with Lv-STK17B plus Lv-shSnail and HCCLM3 cells transfected with Lv-shSTK17B plus Lv-Snail were used to perform further experiments. This evidence concerns the gene SNAI1 and hepatocellular carcinoma.