CHUK and neoplasm: These experiments were repeated with IKKα- and IKKβ-silenced MC38 cells (KrasG13R; MPE-competent) stably expressing pNGL, confirming that IKKα is cardinal for oncogenic NF-κΒ activation and MPE precipitation by pleural-metastatic KRASMUT tumor cells (Fig. 6d–f; Supplementary Table 3).