We found that WT macrophages mixed with CMT93 cells (WTmφ MIX) significantly promoted tumor growth compared with Ndrg2−/− macrophages (Ndrg2−/−mφ MIX) and tumors without the macrophage premix (CMT93), while Ndrg2−/− macrophages showed an attenuated tumor-promoting potential (Fig. 4a). Here, MIXL1 is linked to neoplasm.