In the same study [14], increased succinate concentrations and over expression of GPR91 were found in an MCD diet- fed mouse model of NAFLD and knockout of the GPR91 gene led to attenuation of steatosis and fibrosis in an MCD diet–induced mouse model of non -alcoholic steatohepatitis. Here, SUCNR1 is linked to metabolic dysfunction-associated steatotic liver disease.