ACTN4 and ovarian carcinoma: In relation to its role in chemoresistance, both the high immunoexpression of the ACTN4 protein, and a high number of ACTN4 gene copies, detected by fluorescence in situ hybridisation (FISH), positively correlate with chemoresistance (polychemotherapy with cyclophosphamide, doxorubicin, and cisplatin) of high grade ovarian cancers.