In our research, extrapulmonary ARDS was caused by sepsis, pancreatitis, extrapulmonary trauma etc. We just analyzed plasma MSC-VEC-miRNAs and vWF, VCAM-1, IL10, TNFα levels between 28 days survival and 28 days non-survival group in ARDSp patients in order to reduce the heterogeneity between patients. The gene discussed is VWF; the disease is Sepsis.