Furthermore, we investigated whether the observed signature could be translated to other MDs, such as the milder allelic variant Becker muscular dystrophy, but also genetically separate myotonic dystrophy type 1 (CUG expansion in the DMPK gene), facioscapulohumeral muscular dystrophy (shortening of a subtelomeric repeat unit enabling the production of the toxic Dux4 retrogene) and limb‐girdle muscular dystrophies type 2A and 2B (lack of calpain‐3 and dysferlin, respectively). The gene discussed is DYSF; the disease is myotonic dystrophy type 1.