NOX4 and posterior cortical atrophy: CAFs comprise a highly heterogeneous cell population with different CAF subtypes shown to exert either tumor‐promoting or tumor‐inhibitory effects in PCa.9In vitro data herein demonstrating that Nox4 plays a central role in paracrine‐mediated pro‐proliferative and promigratory effects of activated fibroblasts on PCa cells strongly suggest that Nox4 inhibition will exert antitumorigenic effects.