Similar to single protocols for Nox4 ISH or TGFβ IHC, dual staining yielded a strong increase in Nox4 mRNA levels in the PCa‐associated stroma and a strong increase in epithelial cell TGFβ immunopositivity in cancerous regions compared to adjacent benign areas (Fig. 2 and Supporting Information, Fig. S6). Here, NOX4 is linked to posterior cortical atrophy.