TGFB1 and posterior cortical atrophy: Our previous observations that elevated Nox4 expression is associated with aggressive PCa as defined by biochemical relapse together with experimental findings that Nox4 knockdown is sufficient to abrogate TGFβ1‐mediated activation of prostate fibroblasts, prompted us to further characterize the role of prostatic Nox4 and investigate the potential utility of pharmacological inhibition of Nox4 as a therapeutic strategy for PCa.