In agreement with its benign status the prostate epithelial cell line RWPE1 secreted only very low levels of TGFβ1 and TGFβ2, whereas DU145 and PC3 PCa cell lines secreted significantly higher levels of TGFβ2 and even greater levels of TGFβ1 (>2 ng/ml; Fig. 6a). The gene discussed is TGFB2; the disease is posterior cortical atrophy.