CCR6 and systemic lupus erythematosus: Our overall analysis of these different Th cell subsets in SLE patients based on anti-DNA status indicated that CCR6+ Th subsets, such as Th9 (P = 0.0006) (Fig. 2B), Th17 (P = 0.0274) (Fig. 2D), Th17.1 (P = 0.0084) (Fig. 2E) and CCR6+CCR4−CXCR3− Th cells (P = 0.0179) (Fig. 3C), were significantly increased in anti-DNA+SLE patients.