CHAMP1 and obesity due to melanocortin 4 receptor deficiency: Patient 57 carry an 8.5-Mb 13q33.2q34 deletion encompassing the ID gene CHAMP1 (Fig. 5c), which partially overlaps with deletions at 13q34 found in 6 other patients with syndromic obesity reported by Vuillaume et al. [22] and Reinstein et al. [21].