CD8+CD103+ iTreg treatment also resulted in a significant lower degree of disease activity and chronicity indices (Figures 2B,C), while cGVHD model group and CD8+CD103− cell treatment group mice exhibited typical pathological damage of lupus nephritis, as shown by disease activity and chronicity index scores (Figures 2A–C). The gene discussed is ITGAE; the disease is lupus nephritis.