Upon analysis, expression of the cytokines IFNB1, IFNG (IFN-γ), TNF (TNF-α), TGFB1 (TGF-β), IL1B, IL2, IL6, CXCL8 (IL-8), and IL10 were all significantly increased in ‘mesenchymal’ lung ADC compared to ‘epithelial’ tumors (Fig. 3A). Here, IL1B is linked to medical procedure.