STAT6 and neoplasm: Whereas, in an immune suppressive environment, eosinophils would employ STAT6 to produce CCL17, CCL22 that are known to attract Th2 cells and promote macrophages to develop into a “Type 2” or a “Tumour-associated” phenotype, which are known to be less active against tumours than “Type 1” macrophages50,51.