To better understand RHOU regulation in MM we have investigated its expression on the GEP data (#GSE66293) and on five MM cell lines available in our laboratory, two IL-6 dependent (INA-6 and SaMMi), one that autocrinally produces IL-6 (U266) and two IL-6 independent (H929 and RPMI-8226). This evidence concerns the gene IL6 and Miyoshi myopathy.