TLR4 and parasitic infectious disease: We monitored peripheral parasitemia after infection at G13 in wild-type females and in Tlr4−/− females carrying Tlr4−/− or Tlr4+/− fetuses and found that the Tlr4 genotype in the maternal compartment did not affect the course of parasitemia during pregnancy, irrespective of the fetal Tlr4 genotype (Fig. 2A).