For example, TFAP2A expression was elevated in nasopharyngeal carcinoma, which promoted nasopharyngeal carcinoma proliferation and growth via inducing cyclooxygenase-2 expression [13]; in addition, TFAP2B was reported to be overexpressed in non-small cell lung cancer (NSCLC) tissues and cell lines. Here, PTGS2 is linked to non-small cell lung carcinoma.