To determine whether miR-375 is decreased in leukemic cells as reported in solid tumors [10, 22], we measured the levels of miR-375 in 7 leukemic cell lines, 102 primary AML blasts, and 20 CD34+ hematopoietic stem and progenitor cells (HSPC) from normal controls (NC). Here, CD34 is linked to acute myeloid leukemia.