For instance, mice with atopic dermatitis exhibited fewer symptoms of dermatitis, showed higher levels of helper T cell 1 (Th1) cytokines and unchanged levels of helper T cell 2 (Th2) cytokines such as interleukin 13 (IL-13), enhanced IL-10, and inhibited IL-1β, IL-6, IL-17, and Tumor Necrosis Factor α (TNFα) under the oral administration of such molecules [59]. This evidence concerns the gene TNF and skin disorder.