The participation of CGRP in repair processes within the mucosal layer of the digestive tract has been reported during gastric ulcers [34], and the mechanism of this activity is probably connected with receptor activity-modifying protein (RAMP) 1, which is an element of CGRP receptors localized in the mucosal layer of the stomach and intestine [51]. This evidence concerns the gene CALCA and gastric ulcer.