Interestingly, although tumor infiltrating lymphocytes (TILs) were shown to correlate with pathological complete response (pCR) after neo-adjuvant chemotherapy (NAC) in all breast cancers, a significant correlation between TILs at diagnosis and overall survival was only observed in TNBC and HER2+ breast cancer; however, the reasons for this remain poorly understood [18,19]. Here, ERBB2 is linked to breast cancer.