For example, the Nrf2 activator sulforaphane (SFN), which is a component of broccoli sprouts, or dimethyl fumarate (DMF), an approved anti-inflammatory drug for the treatment of patients suffering from psoriasis or multiple sclerosis, oxidize mainly cysteine 151 of Keap1 [21,22]. This evidence concerns the gene NFE2L2 and multiple sclerosis.