Moreover, WIF1 methylation was inversely correlated with gene expression in CRC (cg03509412, r = −0.326, P < 0.001, cg19427610, r = −0.322, P < 0.001, cg24166864, r = −0.301, P < 0.001, cg21383810, r = −0.033, P > 0.05). Here, WIF1 is linked to colorectal carcinoma.