Apart from that, PI3K inhibitor LY294002 abolished the effect of miR-361-5p on autophagy and chemoresistance to docetaxel of GC cells compared with docetaxel + miR-361-5p mimic group, indicating that miR-361-5p suppressed autophagy-induced chemoresistance by targeting FOXM1 via the PI3K/Akt/mTOR pathway in GC cells. This evidence concerns the gene FOXM1 and gastric cancer.