However, overexpression of miR-361-5p increased the low expression of p-AKT and mTOR caused by docetaxel while overexpressed FOXM1 decreased the expression of p-AKT and mTOR significantly compared with docetaxel + miR-361-5p mimic group, suggesting that overexpression of miR-361-5p activated while overexpressed FOXM1 suppressed PI3K/Akt/mTOR pathway in docetaxel treated GC cells (Figure 5A-5B, P* < 0.05, P# < 0.05, P$ < 0.05). The gene discussed is FOXM1; the disease is gastric cancer.