We then performed Q-RT-PCR and immunoblotting experiments of Shh pathway components in a panel of papillary (TPC1, BCPAP) and anaplastic (SW1736, 8505C, CAL62, OCUT1) thyroid cancer cells compared to immortalized NTHY cell line (derived from non-tumoral tissue). This evidence concerns the gene SHH and thyroid gland carcinoma.