Receiver operating characteristic (ROC) analysis showed that these three markers could discriminate between cancer patients and controls, with an area under the curve [AUC] of 0.68 for CEA (95% confidence interval [CI]: 0.56 to 0.79), 0.78 for CA 19-9 (95% CI: 0.66 to 0.89), and 0.83 for mir-let-7d (95% CI: 0.74 to 0.91). Here, CEACAM5 is linked to cancer.