Although Binsky et al. have recently published that SLAMF5 acts as a survival receptor in chronic lymphocytic leukemia cells and its downregulation results in receptor induced cell death (31), under our experimental conditions neither the viability of moDCs nor the yield of differentiation was affected by SLAMF5 silencing (Figure 1C). Here, CD84 is linked to B-cell chronic lymphocytic leukemia.