The most convincing evidence linking Lsamp with schizophrenia comes from protein studies in the post mortem brains: the level of the LSAMP protein is increased in the postmortem dorsolateral prefrontal cortex (DLPFC) (Behan et al., 2009) and in the synaptosome fraction of the orbitofrontal cortex (Velásquez et al., 2017) in patients with schizophrenia. The gene discussed is LSAMP; the disease is schizophrenia.