LAMA4 and carcinoma: In this study, we found LAMA4 was over-expressed in TNBC, the results were in consistent with a study by Ross et al. They found LAMA4 could promote cancer cell proliferation and increased LAMA4 expression marks the transition of human pre-malignant breast lesions to malignant carcinomas, and tumoral LAMA4 overexpression predicts reduced relapse-free survival in ER-negative patients [30].