Importantly, the seven-miRNA signature was able to predict OS in both IDH1 wild-type (n = 280) and IDH1 mutated (n = 16) GBM patients (P < 1.01 * 10−3 and P < 4.62 * 10−2, respectively; log-rank test) (see Supplementary Figure S2). The gene discussed is IDH1; the disease is glioblastoma.