In particular, the amount of IFNγ produced at 24 hours post-infection seemed to correlate with protection, with Cc-A1AT producing 15 times more IFNγ than virus alone and protecting 86% of mice, Cc-Griffithsin producing 10 times more IFNγ and protecting 57% of mice, Cc-Control providing no protection and producing 4 times more IFNγ and Cc-BmKn2 providing no protection and producing double the amount of IFNγ. This evidence concerns the gene CXCR1 and infection.