The patient described was enrolled into our clinical trial8, LURET (Lung Cancer with RET Rearrangement Study; clinical trial registration number: UMIN000010095, https://upload.umin.ac.jp/), which investigates the efficacy of vandetanib for the treatment of non-small cell lung cancer (NSCLC) with oncogenic RET fusion. This evidence concerns the gene RET and non-small cell lung carcinoma.