BRAF and low grade glioma: For example, BRAF p.V600E has been observed in 25%–35% of adult and pediatric gangliogliomas (Schindler et al. 2011; Qaddoumi et al. 2016), whereas other BRAF genetic alterations and KIAA1549-BRAF and FAM131B-BRAF fusions have also been observed in low-grade gliomas, the former fusion having been identified in gangliogliomas (Dimitriadis et al. 2013; Gupta et al. 2014; Roth et al. 2015).