As performed similarly in A20 lymphoma (Figure S3), three IT injections of CpG(B)-STAT3dODN (1 mg/kg), but not CpG(B)-scrODN or PBS, inhibited STAT3 DNA binding in human OCI-Ly3 lymphoma, as assessed using the EMSA (Figure S4). The gene discussed is CD8B; the disease is lymphoma.