The level of BMI, FPG, 2hPG, HbA1c, TG, TC, LDL-C, 8-OHdG, 3-NT, CRP, SBP and IL-6 in DM group was higher than that in NC group, and the level of GSH, SOD and HDL-C was lower than NC group, both of the differences were significant (P < 0.05). The gene discussed is CRP; the disease is diabetes mellitus.