Interestingly, a significant gene expression pattern of AKAPs was noted relative to tumor PAM50 subtypes whereby AKAP1, 3, 7 and 8 were highly expressed in basal-like subtypes and lower expressed in the other subtypes (p < 0.001 Basal vs. other subgroups, ANOVA with post-hoc Tukey, Additional file 8: Figure S5a and Fig. 3a). This evidence concerns the gene AKAP1 and neoplasm.