CYCS and amyotrophic lateral sclerosis: KEGG pathway enrichment analysis performed on genes differentially expressed in FUSHOMO (Fig. 3d, right panel) identified a molecular pathway named “amyotrophic lateral sclerosis,” composed of three hits, whose deregulation was already associated with ALS: Cyct (cytochrome C) [41], Prph (peripherin) [42–44], and Gria2 (glutamate ionotropic receptor α‐amino‐3‐hydroxy‐5‐methyl-4-isoxazole propionic acid (AMPA) type subunit 2) [45, 46].