In the multivariate stepwise analysis, the OR for the serum level of IL-23 > 0.0 pg/mL in SLE patients with atherosclerotic plaque in the right common femoral artery was 12.67 (95% CI 1.41–113.84), P = 0.023, with obesity was 2.98 (95% CI 0.84–10.61), P = 0.091 (result at the border of statistical significance), with lupus nephritis was 3.69 (95% CI 1.11–12.22), P = 0.033, with the presence of aSS-B/La was 15.43 (95% CI 1.73–137.25), P = 0.014, and with aPE IgG was 11.06 (95% CI 1.24–98.65), P = 0.031 (Table 8). This evidence concerns the gene IL37 and obesity due to melanocortin 4 receptor deficiency.