SALL1 and Abnormal renal morphology: As the hPSCs differentiate toward kidney progenitors in vitro, they expressed the transcription factors PAX2 and SALL1, respectively mutated in the human renal coloboma (Sanyanusin et al., 1995) and Townes-Brocks (Faguer et al., 2009) syndromes featuring kidney malformations.