MPPE1 and neoplasm: The overall importance of cDC1 in anti-tumor immunity is underscored by multiple studies demonstrating that the lack of cDC1 in Batf3−/− mice abolishes the rejection of immunogenic tumors and the response to adoptive T cell therapy and to immune checkpoint blockade (Broz et al., 2014, Hildner et al., 2008, Salmon et al., 2016, Sánchez-Paulete et al., 2016, Spranger et al., 2015).