Tumor infiltration by cDC1s was confirmed by distance analyses after surface reconstruction of cDC1 profiles in confocal images, which revealed that cDC1 in Ptgs1/Ptgs2−/− BRAFV600E melanomas were located further away from the tumor margin and from CD31+ blood vessels than in control tumors (Figure 1F). Here, MPPE1 is linked to melanoma.