Other serum markers such as cancer antigen 19-9 (CA19-9)18,19, cancer antigen 125 (CA125)20,21, cancer antigen 72-4 (CA72-4)22,23, serum ferritin (SF)24,25 have also been used as the indicators for CRC diagnosis and for post-operative surveillance, as well as monitoring treatment effects. Here, MUC16 is linked to colorectal carcinoma.