The magnitudes of the cTfh responses correlated significantly with both the IgA+ plasmablast responses (Fig. 3a, R = 0.77), the total plasma blast responses (R = 0.70, not shown) and the combined index of ALS responses against the five major vaccine antigens (Fig. 3b, R = 0.60). The gene discussed is CD79A; the disease is amyotrophic lateral sclerosis.