With further detection of G1 phase-related molecule expressions, we found that forced expression of ZFP36L1 or ZFP36L2 markedly reduced cyclin D protein expression but did not change expressions of other molecules, including cyclin A, Cdk2, or Cdk4, in these three types of colorectal cancer cell (Fig. 5). This evidence concerns the gene CCNA2 and colorectal cancer.