The aim of the present study was to investigate the potential role of the CYP4F2 (Cytochrome P450 Family 4 Subfamily F Member 2) polymorphism in the risk of cardiovascular and cerebrovascular diseases, such as myocardial infarction (MI), coronary artery disease (CAD), ischemic stroke (IS), cerebral infarction (CI) and hypertension. This evidence concerns the gene CYP4F2 and brain infarction.