To our knowledge, this is the first attempt to investigate the association between Lp‐PLA2 mass and the presence of subclinical atherosclerosis in a general and asymptomatic Chinese population, and the only study addressing the association between Lp‐PLA2 mass and ACAS, ICAS or ECAS in terms of general population levels. Here, PLA2G7 is linked to atherosclerosis.