Out of 5 SNPs specific to PTPN22, rs2476601 was significant in RA since heterozygous (GA) or minor (AA) alleles were detected in 20/70 (28.6%) RA samples compared to only 4/62 (6.45%) healthy controls (p-values ≤ 0.05, Figure 3B). The gene discussed is PTPN22; the disease is rheumatoid arthritis.