We simulated an ischemic stroke and reperfusion scenario by exposing the slices to a 15 min period of oxygen and glucose deprivation (OGD), followed by a 2 h period of re-oxygenation (ReOx) in the absence or presence of the sGC activators, BAY58-2667 (100 nM) or BAY60-2770 (100 nM). This evidence concerns the gene SGCB and ischemic stroke.