Our results showed that p62 overexpression was related to lymph node metastasis (RR = 1.21, 95% CI: 1.06–1.37) and clinical stages (RR = 1.27, 95% CI: 1.12–1.45), which was independent of gender (RR = 1.00, 95% CI: 0.78–1.29), tumor differentiation (RR = 0.86, 95% CI: 0.67–1.11) and tumor status (RR = 1.00, 95% CI: 0.78–1.29) (see Table 3 and Supplementary Figure 1). The gene discussed is SQSTM1; the disease is neoplasm.